A publication on the neurosurgery of today and tomorrow

In a decade, neurosurgery stopped being a matter of force and became one of precision.

This is a journey through the ideas, tools and frontiers redefining how we understand and operate on the human brain.

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01Journal

The brain, in brief.

02Cases that changed paradigms

Not treatments. Clinical reasoning.

Each case, fully anonymized, is told as what it was: a problem, several alternatives and a reasoned decision. The pathology is the example; the focus is how one thinks.

03Technology

Tools that don't change the equipment. They change the decision.

Neuronavegación

A GPS for the brain

Tractography reveals the nerve-fiber 'highways' that must be preserved. The route is planned before the first incision.

Fluorescencia · 5-ALA

Seeing the invisible

The patient drinks a compound that makes the tumor glow pink under a special light, sharply outlining the tissue to be removed.

Exoscopio 4K-3D

A new way of seeing

It replaces the classic microscope with an ultra-high-definition 3D image shared by the entire surgical team.

Imagen intraoperatoria

Confirming in the moment

MRI inside the operating room confirms —without ending the surgery— that the resection was complete.

Monitorización

Listening to the nervous system

Neurophysiology monitors critical functions in real time and warns before a maneuver can harm them.

Inteligencia artificial

A second pair of eyes

From image analysis to surgical planning, AI is beginning to assist decisions that once relied on experience alone.

04Lab

I don't just write about the technology. I also build it.

Interactive tools I build to think about and teach neurosurgery. These are evolving projects —Beta versions— for strictly educational purposes.

Educational and outreach tools. They are not medical devices, do not process patient data and do not replace clinical judgment.

05For patients and families

You are not alone in this.

A careful selection of patient and family associations —in Argentina and worldwide— that support, inform and connect those living with these conditions.

Editorial selection for informational purposes. Inclusion implies no commercial link or endorsement; links open external sites.

06The neurosurgery of today

How brain surgery really changed over the last ten years.

For nearly a century, operating on the brain meant opening it up in order to see. Today, much of the progress lies in the opposite: seeing better to open less —or not at all.

Radiosurgery treats tumors without a single incision. Endoscopy reaches the skull base through the nose. Fluorescence makes a tumor glow to separate it from healthy tissue. These are not gadgets: they are a shift in how decisions are made.

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07The future

Where all of neurosurgery is heading.

Not all of this is part of daily practice —yet. But following the field's evolution closely is part of practicing it seriously.

01

Brain–computer interfaces

In 2025, implants restored speech to paralyzed patients.

02

Adaptive DBS

A brain pacemaker that self-adjusts to the brain's activity.

03

Focused ultrasound

Treating tremor from outside the skull, with no incision.

04

Robotics

Sub-millimetric precision and stability beyond the human hand.

05

Personalized medicine

Decisions guided by each tumor's molecular profile.

06

Digital twins

Simulating a surgery on a virtual replica before performing it.

07

New biomarkers

Detecting and classifying disease with unprecedented precision.

08

Surgical AI

From the OR to predicting outcomes and complications.

Explore the eight fields →
Automatically updated

Neurosurgery now

Source: PubMed · editorial curation

Curated selection of recent literature. The list updates automatically from PubMed (NEJM, Nature Medicine, Journal of Neurosurgery, JAMA) and always links to the original source.

08About
Dr. Pirozzo

I am a neurosurgeon. I devote my work to a discipline that, like few others, demands both technical rigor and human care at once.

I trained at the Hospital Militar Central residency, completed a fellowship in endoscopic skull base surgery at Ohio State University and specialized at UBA. Today, beyond operating, I lead and teach. This publication is my way of sharing where all of this is heading.

Dr. Mariano PirozzoNeurosurgeon · MN 119.938
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